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Web-based tools
(Lange lab developments)

BioPathAt
Biochemical pathway maps for integrative analysis of post-genomic data sets

MGR
Genome and transcriptome database for members of the mint family

Spektraris
Accurate mass - time tag (AMT) and NMR library for plant natural products

Research infrastructure

M.J. Murdock Metabolomics Laboratory
Analytical center for metabolomics research

 

 

 

The Lange laboratory investigates the biosynthesis of plant natural products (with an emphasis on terpenoids) using functional genomics and systems biology approaches. We are developing mathematical models to quantitatively describe the regulation of metabolic pathways. Our models enable knowledge-based pathway improvements by breeding or metabolic engineering.

We are particularly interested in understanding metabolism in specialized plant cell types, which are responsible for the synthesis of essential oils, oleoresins, and pharmaceutically relevant natural products.

Group Meetings
Friday, April 25, 2018.........................................................................................................2:00 to 4:00 PM
Friday, May 4, 2018............................................................................................................1:00 to 4:00 PM

Lab Seminar
Wddnesday, April 25, 2018
Jana Richter.........................................................................................................................1:00 to 2:00 PM

Group members (September 23, 2016)

Back row, left to right:
Jordan Zager, Kellen Mayes, Fima Inabuy.

Front row, left to right:
Mark Lange, Iris Lange, Narayanan Srividya, Amber Parrish, Dunja Samec, Sean Johnson, Brenton Poirier.

Not on photo:
Sophiya Chayka, Richard Schumaker.

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..Last updated:
April 17, 2018

Lange Laboratory News:

2018 (March 14)
Chanchan Liu (center, with present) has her last day as a visiting graduate student. She is going back to China to finish her dissertation. All the best, Chanchan!

2018 (March 10)
Our paper reporting on the developmental dynamics of essential oil biosynthesis in Japanese catnip (collaboration with Dr. Qianan Wu and colleagues at
Nanjing University of Chinese Medicine) is published online in Phytochemistry (WebLink to article).

2018 (February 23)
Mark Lange gives an invited lecture at the Cornell University in Ithaca, NY.

2018 (February 6)
Our mass spectrometric analyses of novel intermediates of coenzyme M biosynthesis in
Xanthobacter autotrophicus, which are part of collaborative efforts with John Peters' lab at teh IBC, are published online in Journal of Biological Chemistry (WebLink to article).

2018 (February 4-9)
Mark Lange serves as Co-Chair for the Gordon Conference on Plant Volatiles in Barga, Italy.

2018 (January 24)
Mark Lange gives an invited lecture at the Annual Conference of the Mint Industry Research Council in New Orleans, LA.

2018 (January 12)
Mark Lange gives an invited lecture at the Oregon Mint Convention in Gleneden Beach, OR.

2017 (December 5)
Mark Lange gives an invited lecture at the Washington Mint Convention in Yakima, WA.

2017 (November 18)
Our review article on plant tissue culture for specialty chemical production is published online as part of the book Biotechnology of Plant Natural Products (WebLink to article).

2017 (November 7)
Fima Inabuy defends her dissertation at 10 AM, in CUB 406. Congratulations, Dr. Inabuy! (Fima is in the center of the first row in the photo below).

2017 (August 24)
Our paper reporting on the bioenergeticts of monoterpene biosynthesis in mint glandular trichomes is published online in Plant Physiology (WebLink to article).

2017 (August 4-9)
Mark Lange assumes the
presidency of the Phytochemical Society of North America at the Annual Conference in Columbia, MO, USA.

(giving out awards - the fun stuff!)

2017 (July 18)
Our paper reporting on the development of Tripterygium adventitious root cultures for the production of pharmaceutically relevant diterpenoids is published online in Plant Physiology (WebLink to article).

2016 (June 24-28)
Fima Inabuy presents a poster at the Annual Conference of the American Society of Plant Biologists in Honolulu, HI.

2017 (April)
Mark Lange co-authors a commentary on a report by the National Academy of Sciences on genetically engineered crops. The article is published in Nature Biotechnology (WebLink to article).

2017 (February)
Our paper reporting on the draft genome sequence for a diploid mint model species (collaboration with Kelly Vining at Oregon State University and Shannon Straub at Hobart and William Smith Colleges) makes the cover of Molecular Plant (WebLink to article).

2017 (February 21)
Mark Lange gives an invited presentation at the
Temasek Life Sciences Laboratory, National University of Singapore.

2017 (February 11-14)
Mark Lange gives an invited presentation at the Phenomcis 2017 conference in Tuczon, AZ.

2017 (January 25)
Mark Lange gives an invited presentation at the Annual Conference of the Mint Industry Research Council in San Diego, CA.

2017 (January 23)
Chanchan Liu (from Nanjing University of Chinese Medicine in China) joins Lange laboratory as a visiting graduate student. Welcome, Chanchan!

2017 (January 13)
Mark Lange gives an invited presentation at the Oregon Mint Convention in Gleneden Beach, OR.