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Genetics 301 Homework Assignment #11, Spring 2003

What are the advantages and disadvantages of the following research organisms for developmental genetics research: Mouse, yeast, Drosophila, C. elegans, Arabidopsis? Consider ease of rearing, ease of visualizing development, ease of conducting experimental matings, and relevance of studies to other "important" organisms".

Distinguish between a cell lineage and a fate map in the description of development.

Which of the following types of mutations are most likely to lead to a homeotic mutation in Drosophila? (more than one may be applicable)

  1. mutation in a transciptional activator (DNA binding) protein.
  2. mutation in a "housekeeping" gene coding for a metabolic enzyme.
  3. mutation in an enhancer adjacent to a gene.

Also: Homework Problems 12.4, 12.7 and 13.2.